ABSTRACT
Before the Pacific War, the Second World War, Yoshitomi Pharmaceuticals was formed as a joint venture between Takeda Pharmaceuticals, which was the number one pharmaceutical company at the time, and Mitsubishi Chemicals, which was the number one chemical company. Clozapine was developed in this country by Dinippon Pharmaceuticals, but they stopped because of ripples from the problems with agranulocytosis overseas. Carpipramine still sells in Japan, but there has been a problem with Japanese pharmacoeconomics: the people have a system whereby the price of pharmaceuticals reduces year by year. Finally, there is the fact that the major companies targeting the psychotropic market don't have antidepressants in their product line, which may have affected the low sales in Japan. Japanese people are very careful about their health. There is a great deal of confusion and depression, which is part of the reason why the Japanese stock price has gone down. .
