ABSTRACT
I came up to Edinburgh in 1956, having just come out of the army. I came up to do the membership course in medicine. Whilst I was up here, there was a job advertised in psychiatry and, as I’d always intended going into psychiatry eventually, I went in slightly earlier than I’d intended. I came at an exciting time because reserpine was already in use, chlorpromazine was just coming into use and the monoamine oxidase inhibitors and Tofranil followed in the next year or so. So, it was an exciting time. I became interested in why reserpine produced depression and why the antidepressant drugs worked.
