This chapter focuses on the question of the ways in which North American experience of religious encounter with indigenous peoples, both at home and overseas, influenced British missionary outlooks and enterprise from the 1790s, when the modern missionary movement finally got under way, to the 1840s, when it entered its second great wave of expansion. The influence, for example, of American revivalism on British evangelicalism had critical consequences for British missionary operations in many parts of the world in the years after 1870. In the later nineteenth century, events in India, China, and parts of Africa impinged on each other to influence missionary strategy in important ways. There seems no obvious reason why such cross-currents should not have been equally a feature of the early century. North American experience could offer insights into the problems of dealing with “savage” or “barbarous” peoples, as well as those of managing white expansion.