This chapter explores the disruptive nature of artificial intelligence (AI) and the nature of work in the future (or, as it has become customarily referred to as “the future of work”). The discussion in this chapter is done under the backdrop of a wider perspective on how technology influences the home and, therefore, the focus on employment relates to how people work and live. Although AI has real potential to contribute to addressing more effectively large-scale challenges, such as healthcare, humanitarian crises or climate crises, risks linked to widespread and indiscriminate use related to data privacy, identity, cyber-security and the like are also real and expose the negative side of AI. Combined, all these challenges and opportunities coming out of the rise of AI may have significant implications on how the “home” will function in the near future as well as the place of work. This chapter offers just a glimpse into the vast possibilities this change may bring.