This chapter focuses on Occupational Safety and Health Administration (OSHA), Americans with Disabilities Act (ADA), and Other Government Mandates as they relate to nonprofit arts organizations. It begins with an exploration of governmental mandates, laws, rules, and regulations. In contrast, policies and procedures within the organization are also covered. The discussion then centers on the OSHA, how the administration works, how one must follow OSHA mandates, and how penalties can be assessed if OSHA rules are not followed. After an overview of possible penalties for nonobservance of the guidelines, the chapter concludes with recommendations and questions for the reader’s consideration. The chapter includes case studies and other pedagogical tools to facilitate teaching and learning.