The WHO reports that during the pandemic every 40 seconds someone committed suicide in one part of the world. Globalization is causing people to work midst paradoxical tensions that simultaneously are flattening and rounding, uniting, and detaching, the connections between and across organizational ecosystems, stakeholders and resources. Technology that includes information and communication tools has been transforming workplaces the world over for years now and will continue to do so in the future. The new generation of employees entering the labor force in the next decades will differ not only in the level and specialization of knowledge and skills they possess, but also in their work attitudes and preferences for work-life balance. Beyond contexts related to business, we are also facing global challenges threatening our sheer existence: demographics and global migration; environmental deterioration through global pollution; climate change; asymmetric conflicts and wars.