ABSTRACT

Heart-lung and lung transplantation have become acceptable interventions for paediatric patients with end-stage cardiopulmonary or pulmonary disease[1]. While transplantation may prolong life in many patients, exercise capacity has been shown to remain well below normal[2]. Furthermore, little is known about the effects of transplantation on aerobic fitness, pulmonary function, and quality of life in the extended months following surgery in paediatric recipients. Consequently, the purpose of this study was to make serial assessments of these variables at standard points in time, specifically 4, 12, 24, and 36 mo following transplantation.