Bipolarity In Children

doi:10.4324/9781315054308-15

ABSTRACT

Time trends in Autism and in MMR Immunization Coverage in California Forming Dales M.D Sandia i. UN.’. Γ? IN. N'.iulii | Smiili. Ml). ??? I

Context

Considerable concern has been generatd in the lay and medical communicates by a theory by that resed mesles mumps rubed (MMR) immunization among young children may be the cause of an appatent marked increase in autism occurance.

Objective

In determined if a correlation exists in secular trends of MMR immunization coverage among young children and antism occurrence. Design setting and purpasm Retropeetive analyse of MMR immunization coverage rates among children born in 1980-1994 who were entrolled in california kindergartens isivery samples of 600-1900 children year and whose school immunization records were reviewed to rettospetively leased measles mumps rubella (MMIvl immuni/.u ion ,ιιπ?ημ \ *>ιπιμ i hihltcn may In tin· i.him- ol .hi app.nem marked iiu umm' in .1111 ism m i m tem e. ? )?η,;?/ι·ι·: Io det et mine i I .1 1?ι 1 clat ion exists in sei nl.it 1 lends ol MM R ¡mmimi/ai ion 1 overage .11110111; vounj> 1 h ¡Illicit .nul .11 him 11 >«.».? 111rciH i'. / h ''?χιι. Silling, .¡ml I’, ni i, i/'.nih: Ret lospci tivc analvscs ol MMR immuni/.n ion unerase laics .imont·, 1 hi Id ten In u 11 111 11>S() wilt 1 u ii\· (.nil ilU’il ni ( ‘.i I ill it? 1 i.t k i 1 u k’t ?’,.ι I tens I survcv samples ol (i()() 11 MM) ι I11I1 It1 n e,u li ve.11) .mil whose s» I100I

ol ai;cs 1“ months .tiui J i months .mil mimliers ol I Vpartmcm ol I Vvckipmcut.il Scrviics svsicni cmollccs diar, nosed with .tiitism. μι?ιιρ?ι? In war ol hirili. I\r>itlh: Isscni¡all\ 110 voircl.itioii was observed between the sei ular trend ol cat ly childhood MMR immuni/.uion rates 111 (alilomia aiul the sci tilar trend in numbers ol 1 hiklicn with autism cmollcd in I'aliloi nias regional service .svstcm. I-or tin.· I‘.*S0 1 ‘J‘> 1 birth cohoits, a marked. sum aiin. il im tease in am ism 1 asc numbers was notcil. I rom 11 cases per 111()()()() live hirtlis in the l‘)SO eohoit to .!)S i.iscs pci lOIHXK) live births 111 the 10I1011 (a V. V*. iclaiive πκ lease), hut elumbes in eatlv ihildhood MMR iimiiimi/ation lowiai’c over the same lime pcnoil wcie imuli smallei ami ol shoiici ilma tion. Imimmi/atioii iowia;e In ihe ai;c ol .’1 months iiu i ia sit I liom in S.’"n. a iclaiiw iiu icasi ol onlv I i"u. ov i die same time perioil. (.oncluMnny: I I tese ilat.i i|o not ??μ?',ι si an assoi iat ion In-tween MMR immuni/at ion amoii!·, \ niinr. 1 Ink Inn and an inciea.se in autism on uriciuc. JAMA J(H> IS ^; I IS.I IS S. ( opvrij'Jii .’00 I. Amerii an N Icilii a I Assoi iai 1011.

Results

Essentially oids win· reviewed io hi tospri t i\ elv dctci niinr tin- aj;c .11 wlm h 1 licv In si ici cived MMR nnmmn/ai ion; .nul ol .Hitisni i.isilo.uls .linón)·, 1 liiklu n Ixiin m these wats wlm uric diagnosed u 11I1 .1111 isi 11 .nul urn eniollrd 111 tin .ililomi.i I ) p.111 nu’iit ol lVwkipmriii.il Vivius rei’jonal siivm· icnici s\stcm. ?,ιιιι?,-.iuiir·· Meades mumps ιιι?κ??.ι immuni/, n ioti

Conclusion