ABSTRACT
The normal biodistribution pattern of 131 I-m-iodobenzyl-guanidine in man and followed by serial scintigraphy showed uptake in salivary glands, liver, spleen and bladder. Less frequently heart, lung and colon activity was observed. Thyroid is also visible when blocked. Double-tracer scanning with an Anger camera and computerized image subtraction was performed in 61 patients whose clinical and biochemical findings had suggested primary hyperparathyroidism. Dissolution and resorption of commercially available 131 I-Nal therapy capsules were investigated in 25 patients before radioiodine ablation of the thyroid because of thyroid carcinoma. In 8 cases a fixation of the capsules in the fundus region was seen with radioactivity discharge in this region. The uptake of 131-Iodine in haemodyalasis patients was studied with the help of the perchlorate discharge test. One hour after administering perchlorate the radioiodine uptake was found to be higher than in a control group. The saliva to plasma ratio of 131-Iodine was also higher in patients with chronic renal failure.
