ABSTRACT

The gastric turnover of pertechnetate was measured in vivo in human subjects and compared with water, sodium and hydrogen ion kinetics. Pancreas and Salivary gland uptake in the rat was observed to be high. At 20 min.pi 3.8% inj.dose/g pancreas was observed and 4.4% at 30 min.pi. The pancreas to liver ratios were 1.9 and 2.5. Similar results were observed in hamsters. Fasting enhanced pancreas uptake even more when followed by a protein rich meal. However the smaller amount of this fraction in the heat treated sample implies a selective loss of ferritin forms during isolation procedures which include heat treatment. The radiation dosimetry for a wide range of reagents and labelled foods used in gastro intestinal diagnostic procedures is reported. The radiation burden for the stomach, small intestine, upper and lower large intestine, Gall bladder, Gonads and total body is given separately for each reagent.