This chapter reviews a research programme on the effects of humour in advertising on positive and negative brand associations and brand choice, and integrates the findings into a single overarching model. Based on the Associative and Propositional Processes Model of Evaluation (Gawronski & Bodenhausen, 2006, 2007, 2011), we propose that repeated pairings of a novel brand with brand-unrelated humour forms positive brand associations, which mediate spontaneous brand choice. This associative process was found to be independent from the level of distraction posed by humour and from awareness of the stimulus pairings. In fact the distraction posed by humour benefits persuasion by preventing negative brand associations. Previous marketing research, which mainly viewed humour as a cue in peripheral processing, was rather pessimistic about the persuasive impact of humour. In contrast, this research programme suggests that a repeated pairing of a brand with humour affects the brand’s underlying associative structure, which may lead to stable attitude changes that guide overt spontaneous brand choice. Theoretical and practical implications are discussed.