ABSTRACT
Tumours of bone and soft tissue are classified based on their principle cell type, and have been classified by the World Health Organization (WHO). Swelling and tenderness over the affected bone are the common findings but there will be limitation of joint movement if there has been irritation of the joint by the tumour, or the tumour has grown into the joint. The differential diagnosis of a bone abnormality depends on the age of the patient, the location of the lesion and the radiographic or magnetic resonance imaging (MRI) characteristics of the lesion. Biopsy remains the gold standard for obtaining a diagnosis in an abnormal lesion of bone. Multimodal neoadjuvant chemotherapy in Ewing's sarcoma produces a dramatic shrinkage of the tumour and reduction in symptoms. Lipomas are the common soft-tissue tumours occuring in middle to old age but sometimes in children and adolescents. Fibrous tumours represent a spectrum of disease from benign to high-grade neoplasms with similar microscopic appearances.
