ABSTRACT

This chapter argues that any fundamental theory of biology must describe the physical basis of enzymatically controlled hereditary processes which possess the reliability necessary for evolution, and that this will require what amounts to a deeper understanding of the quantum theory of a molecular measurement process. The reliability of substrate recognition and the speed of catalysis become a problem of describing how dynamical correlations can be maintained without invoking classical structures. Such reliability consideration will probably be crucially related to the size of enzymes and the structures associated with hereditary transmission, which of course includes the machinery for DNA replication and transcription as well as coding. By molecular biological description we shall mean the use of such concepts as the template replication of DNA, the transcription of the genetic message from DNA to messenger RNA, the translation of this coded message to amino acids, and the synthesis of proteins.