ABSTRACT

This chapter discusses how transient receptor potential (TRP) channels can regulate both female and male fertility in different species and their specific roles. TRP channels play crucial regulatory roles in many physiological processes, including those associated with reproductive tissues. Sperm development begins in the male reproductive tract, which consists of the testes, epididymis, and ejaculatory duct: vas deferens and urethra. The process of male germ cell differentiation in mammals, that is, spermatogenesis which takes place in the seminiferous tubules of the testis. The first post-testicular maturation step takes place in the epididymis where the lipid and protein structure of the sperm membrane is further modified to enable the cell to react to signals in the female reproductive tract. Upon ejaculation, sperm cells are mixed with fluids from prostate and seminal vesicles, which, combined with fluids from the testis and epididymis, create seminal plasma.