This chapter offers an analysis of non-governmental organizations (NGO) and their performances in conflict zones, their adaptation to the transformation in crisis management and conflict transformation, their established and new roles, and how this impact the relations with states, in the context of intergovernmental organisations, particularly at United nations and European Union level. The influence exerted by NGOs in several policy fields has increasingly grown and diversified. The theoretical framework has highlighted major changes in the global and regional context, but also the fact that this brings for NGOs deployed in the field a mixture of traditional humanitarian tasks, innovative duties additional risks. The strengthening of security conditions for NGOs, for other aid workers, should enter the political agendas of international and regional organisations and be part of debates on conflict management and external interventions. There are two internal factors which are the result of these developments in how NGOs approach and face the conflicts and which can impact their security.