ABSTRACT

Nail fungal infections frequently addressed as onychomycosis present a considerable prevalence on the global population. Onychomycosis often causes discoloration, thickening and detachment from the nail bed, leading to eventual destruction of the nail bed and inducing important psychosocial and physical detrimental effects. Onychomycosis is an ailment that has several different risk factors. As for age, it is reported that onychomycosis is more prevalent at older age, being the elderly the most affected population with an age/infection correlation of 20" and up to 50" of subjects over 60 and 70 years old, respectively. Distal and lateral subungual onychomycosis is the most common type of onychomycosis. Superficial white onychomycosis presents itself as opaque white patches along the dorsal surface of the nail plate. Total dystrophic onychomycosis is usually considered the end stage of any other type of onychomycosis. Creams are semi-solid topical preparations used for delivery of one or more active substances, or for their emollient or protective action.