ABSTRACT

As noted in previous chapters, humans are exposed to a variety of substances, by ingestion, inhalation, and dermal contact. Unlike the general population, however, workers are often exposed to higher levels of specific toxicants. Such exposures may clearly result in adverse effects. In fact, as early as 1775, Pott observed that chimney sweeps exposed to soot developed cancer of the scrotum. In 1895, Rehn discovered that bladder tumors occurred among workers in aniline dye factories.