ABSTRACT

The fact that all information from patients and treatment outcome, collected and analysed in a central laboratory means a permanent exchange of data between bench and bedside. This chapter addresses some premises for efficient treatment strategies, which may help to improve medical care in these patients, and then offer such a clinical approach, which has recently been developed in Trier. Since a reasonable diagnostic assessment of relevant central and peripheral determinants of stress-related disorders would not be manageable in a clinical setting, we decided to focus solely on the interfaces, which participate in the crosstalk between the brain and the body. Thus, could considerably reduces complexity and heterogeneity and bypass the missing covariance, since monitoring the activity of the interfaces allows us to assess directly stress effects on the brain-body communication. The five strategies addressed in the chapter shows how challenges for neurobehavioral medicine can be met practically.