ABSTRACT
This chapter looks into the results of Genome-Wide Associations Studies, one of the leading trends in molecular psychiatry. The main reason for their limited achievements to-date is precisely what they have been designed to handle: complexity. Yet this much used term needs further clarification in the context of Genome-Wide Association Studies. A distinction should be made between 1) unreliable phenotypes, a problem that may eventually solve itself with a molecular approach, 2) complex inheritance processes, and 3) complex mechanisms, in the forms of genomic, etiological, and pathophysiological complexity. This situation is of interest to the study of several traditional questions in the philosophy of medicine.
