This chapter reviews the contribution that couple relationship education (RE) can make for couples at various points in their relationships. RE provides couples with knowledge and skills to enhance their relationship and prevent future relationship distress. There are a number of life events when RE might be beneficial, and couples could be receptive to engaging in RE. Health crises occurring in one partner impact upon not only the individual sufferer but also partners. The transition to parenthood is another window of opportunity for couples to utilize RE. New parents are faced with a range of challenges, and it is a high-risk time for deterioration of couple adjustment. Several studies demonstrate that RE can be delivered successfully using online programs. However, some professional contact is usually beneficial, as attrition from online programs tends to be a challenge when there is little or no professional contact.