ABSTRACT

A 3-dimensional sculpture can be realised via two fundamentally opposing stratagems or approaches. New neurones, connection and circuits are added, typically during early in utero phases. Subsequently, maybe during the first few months or years of a baby's existence outside of its mother, inappropriate, unwanted or no longer necessary neurones or connections may be discarded, lost, by a process of developmental or programmed apoptosis or culling. It cannot be contested that the very general architecture of the human brain is largely similar for every individual, with particular neurones, circuits, networks and areas largely responsible for certain brain functions. Brain functions such as, perhaps, sensory and perceptual processes, cognitive aspects, drives and emotions, motor mechanisms, and in our own highly social species, maybe also social and group behaviour. Psychiatric pathology can therefore stem from maldevelopment of structure or function, and also from changing societal expectations or norms.