This chapter links the experiences of the global South and the global North by showing that the everyday effects of neoliberal globalization and resistances to it share commonalities across the world, independently of where one lives. It discusses the alter-globalization process, in order to link global resistances to neoliberalism with concrete local experiences of collective resistance. The chapter reviews neo-Gramscian, Marxist and postcolonial approaches to hegemony and resistance. It offers an alternative proposal, derived from experiences of social mobilization in concrete local settings in Argentina and Bolivia that invite us to think about the encounters between local and global practices and dynamics in the exercise of resistance against neoliberal globalization, as well as some final insights that might be drawn from this approach. The global demonstrations of the initial period were primarily aimed at the implementation of neoliberal policies and specifically targeted world summits on economic and financial issues.