This chapter deals with socio-spatial differentiation in Prague after transition. The empirical evidence shows decreasing segregation indices for the whole of the twentieth century, so this decrease cannot be ascribed solely to the period of post-socialist development. The process of professionalisation has flattening effects within the higher-status groups and has led to a decreasing share of lowerstatus groups in Prague’s population during the last decennia. The decrease in socio-spatial differentiation is mainly a consequence of the location of new housing and in-migration of higher-strata groups into formerly poorer neighbourhoods. Moreover, the high price of housing has restricted the in-migration of the economically weak population. Thus we cannot find larger poor areas in contemporary Prague.