ABSTRACT
The Gilles de la Tourette syndrome (GTS) is a chronic and complex neuropsychiatric disorder defined by the cardinal features of fluctuating motor and phonic tics. A range of behavioural and cognitive disorders often accompanies these tics. Although the precise pathogenic mechanisms remain unclear, a picture is emerging from accumulated evidence that, in most cases, GTS occurs in those individuals with a genetically determined vulnerability. Tics usually begin in middle childhood with motor tics often preceding the onset of phonic tics. Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neuropsychiatric syndrome of childhood onset. Children with ADHD are typically described as having chronic difficulties in the areas of inattention, impulsivity, and overactivity. Epidemiological studies suggest that ADHD may be among the most common childhood psychiatric disorders. The ADHD children in this study generally performed normally on the various tests of frontal lobe dysfunction.
