ABSTRACT

As a genetic experiment of nature, Williams syndrome (WS) is expressed on multiple biological levels. Ultimately, WS presents an unusual neurobehavioral profile, affording the opportunity to study both neurobiology and neuropsychology within a single, genetically defined paradigm. The Salk Institute’s Laboratory for Cognitive Neuroscience (LCN) has been engaged in a comprehensive program of study that spans multiple biological levels in WS. These levels include the linguistic, the neuropsychological, the neuroanatomic, the neurophysiologic, and the genetic. The fundamental goal of these combined investigations is to help elucidate the brain bases of behavior.