Is anti-racism a useful method to understand racism’s morphologies today? This chapter attempts to respond theoretically, and by drawing on the archive of historical struggles against racism, to the challenge that contemporary racism poses on us in its transformation across time and space. Understanding (a) racism as an episteme allows us to develop (b) a relational understanding of racism, and (c) one that analyses the current conjuncture of racism as one determined, organised, and reorganised though struggle – in social and political confrontations that produce, reproduce, and transform their opponents (which can be manifold) in their identity and formation. The chapter engages with anti-racism as part of labour history, in the colonial context, and in migration struggles, and what this means for a method of inquiry, and as a perspective of inquiry to come to terms with the variegated space and heterogeneity of racist articulations and practices in our world.