ABSTRACT

Currently, cholinesterase inhibitors (ChEI) represent the treatment of choice for Alzheimer’s Disease (AD) (Fig. 6.1). Following the 1980s introduction of a first generation of drugs such as physostigmine and tacrine, a second generation of more suitable compounds was developed in the 1990s. These drugs are clinically more efficacious and produce less severe side effects at effective doses. Treatment of Alzheimer Disease. Which Way to Go? https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9781410607225/458418f2-25be-4366-87d2-6ed2617fe83a/content/fig6_1_B.tif" xmlns:xlink="https://www.w3.org/1999/xlink"/>