ABSTRACT
Other chapters in this volume describe nonadherence's impact on health treatment and describe methods for its prevention. In this chapter, we describe the impact of nonadherence on the interpretations of clinical study findings. This newer statistical literature is characterized by a wide diversity of methods not easily implemented using standard software packages. Accordingly, our intent in this chapter is to convey key statistical concepts using simple examples without focusing on computational and implementation issues. Readers interested in a more technical discussion will find references to more advanced treatments toward the end of this chapter. The reader will also find a glossary of key terms at the end of this chapter.
