ABSTRACT

Epigallocatechin gallate (EGCG) is a catechin abundantly present in green tea. It exerts multiple therapeutic effects, such as antioxidant and metal chelation, and can effectively treat progress of neurodegenerative diseases such as Alzheimer’s disease (AD). Although it is very effective at inhibiting the pathological events of AD, several limitations, such as instability, low bioavailability, and short systemic circulation period, impedes its success profoundly. With a view to overcoming these issues, a number of nanotechnological methods are currently under evaluation. This chapter highlights the therapeutic benefits of EGCG, its limitations, and currently used nanotechnological methods for enhancing the therapeutic efficacy of EGCG.