ABSTRACT

Analyzed mAChR KO Mice............................................................127 5.3.4 Generation and Analysis of mAChR Double KO Mice..................128

5.4 Relevance for Drug Therapy........................................................................129 5.4.1 M

Receptors....................................................................................129 5.4.2 M

Receptors....................................................................................129 5.4.3 M

Receptors....................................................................................130 5.4.4 M

Receptors....................................................................................130 5.4.5 M

Receptors....................................................................................130 5.5 Conclusions and Future Outlook .................................................................131 Acknowledgments..................................................................................................131 References..............................................................................................................131

The individual members of the muscarinic acetylcholine receptor (mAChR) family are prototypical members of the class A subfamily of G protein-coupled receptors (rhodopsin-like GPCRs).