ABSTRACT

Introduction About 50% of women with breast cancer and *70% of men with prostate cancer are diagnosed after the age of 65. Hormonal therapy rarely causes acute side effects and is often recommended in senior patients with breast and prostate cancer. However, hormonal agents are associated with chronic toxicities that can sometimes be life threatening. Thus, before recommending hormonal therapy to elderly patients, the benefits of treatment should be balanced against potential harms and competing risks of morbidity and mortality.

Breast Cancer In women older than 65 years (and in men with breast cancer), approximately 90% of cancers are estrogen receptor (ER) and/or progesterone receptor (PR) positive.