In genetic female foetuses with classical congenital adrenal hyperplasia (CAH), the adrenal gland’s overproduction of testosterone produces varying degrees of virilization of the developing external genitalia. Genetic female infants experiencing a salt-wasting crisis after birth will be diagnosed as having CAH, and will be most usually assigned female, with surgery/hormone treatment to ‘feminize’ their ambiguous or fully virilized genitals. Jessie, who was named sometime after her birth, had no vaginal opening, an enlarged clitoris and almost-separate labia. An ultrasound indicated the presence of a uterus and ovaries, and a genetic test revealed that Jessie is a genetic female. Sal is about twenty years older than Kellie and Jessie, and describes the clitoral amputation she went through at three months of age as ‘traumatic’. Creighton called for a long-term study of the outcomes of surgical management of conditions such as Congenital Adrenal Hyperplasia exactly because that management remains controversial.