ABSTRACT

Bioadhesion and Drug Delivery Mark E.Byrne, David B.Henthorn, Yanbin Huang, and Nicholas A.Peppas

Purdue University, West Lafayette, Indiana

I.INTRODUCTION: SURFACE MODIFICATION OF POLYMERIC MATERIALS

Polymer surfaces in contact with biological fluids, cells, or cellular components are normally tailored to provide specific recognition properties or to resist binding depending on the intended application and environment. The specific surface chemistry and topography directly influence a favorable recognition event (1). Engineering the molecular design of biomaterials by controlling recognition and specificity is the first step in coordinating and duplicating complex biological and physiological processes (2, 3).