ABSTRACT

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Quantitative Biology: From Molecular to Cellular Systems edited by Michael E. Wall © 2012 CRC Press / Taylor & Francis Group, LLC. ISBN: 978-1-4398-2722-2

9.1 Introduction to Genetic Parts Genetic parts are the most fundamental units of DNA in synthetic biology. ey are dened by their sequence, which can be inserted into a specic location upstream, downstream, or within a gene to achieve controllable expression. By changing the DNA sequence of a part, the expression properties of its target gene such as expression level, specicity to a regulator, or response time can be altered. e precise control of these properties with parts is vital for connecting and rewiring genes into synthetic genetic circuits [1,2].