ABSTRACT

The primary neuroimaging techniques used to assess brain structure and function are presented in the top and bottom panels. A great variety of neuroimaging techniques, behavioral tasks, and data analyses have been applied to date in the study of timing, yet firm conclusions from this mass of data remain elusive. Indirect evidence for the involvement of the right putamen in interval timing comes from a study of motor sequencing. A photomultiplier then records the number of photons that are reflected back through the skull and scalp, and the transmission time gives information about the degree of scattering and absorption of the signal. The formal method to perform a group analysis of activated neural regions is to transform functional data from individual participants into a standard coordinate system, such as Talairach space, and average the voxel-wise time series. The signal returns to baseline after another 6 to 8 sec, and this extended time course of activation is termed the hemodynamic response.