ABSTRACT

Cancer is a major health problem around the world (1). In the United States,

cancer is the second leading cause of death, exceeded only by heart disease, with

one of every four deaths in this country due to cancer (2,3). Over the past two

decades, improvements in the five-year survival rates have been observed for

some of the more common cancers in developed countries, presumably as a result

of increased screening, earlier diagnosis, and improvements in initial treatments

(3). As a result, there is an increasing population of cancer survivors, i.e.,

individuals who have successfully completed initial therapies but who are at

increased risk for recurrence or new cancers, when compared with those who

have not been diagnosed with cancer.