ABSTRACT
The last 20 years have seen unprecedented changes in the pattern of fungal infection in humans. These infections have assumed a much greater importance because of their increasing incidence in patients with the acquired immunodeficiency syndrome (AIDS), in transplant recipients, in cancer patients, and in other groups of debilitated or immunocompromised individuals. New pathogens have emerged, while others that once were common have almost been eradicated. Major changes in medical practice, increasing international travel, and misuse of antimicrobiol agents, are among the factors that have contributed to this changing pattern of fungal infection. New drugs have been developed, resulting in a choice of treatment depending, to some extent, on the infection and the underlying condition of the patient.
