ABSTRACT

Other common trade names: Chol-Less; Colestrol; Lismol; PMS-Cholestyramine; Prevalite; Quantalan; Questran Lite Indications: Pruritus associated with biliary obstruction, primary hypercholesterolemia Category: Antidiarrheal; Antihyperlipidemic; Antipruritic (cholestasis) Half-life: N/A Clinically important, potentially hazardous interactions with: acetaminophen, acitretin, aspirin, chloroquine, cyclosporine, digoxin, doxepin, hydroxychloroquine, isotretinoin, lovastatin, mycophenolate, raloxifene, sulfasalazine, tetracycline, valproic acid

Reactions

Skin Edema Exanthems Rash (sic) (<1%) Urticaria

Hematopoietic Ecchymoses

Other Dysgeusia Osteomalacia [1] Paresthesias Tinnitus Tongue irritation (<1%)

Synonym: OPC13013 Trade name: Pletal (Pfizer) Indications: Peripheral vascular disease, intermittent claudication Category: Platelet aggregation inhibitor Half-life: 11-13 hours Clinically important, potentially hazardous interactions with: clarithromycin, erythromycin, fondaparinux

Reactions

Skin Chills (<2%) Edema (<2%) Facial edema (<2%) Furunculosis (<2%) Hypertrophy Infections Peripheral edema (7-9%) Pruritus Purpura (<2%) Rash (sic) (2%)

Urticaria (<2%) Xerosis (<2%)

Hematopoietic Ecchymoses (<2%)

Other Headache Hyperesthesia (2%) Myalgia (2-3%) Paresthesias (2%) Tongue edema (<2%) Vaginitis (<2%)