ABSTRACT
Trade name: Ismelin (Novartis) Other common trade names: Apo-Guanethidine; Ismeline Indications: Hypertension Category: Alpha-2-adrenoceptor blocker; Antihypertensive Half-life: 5-10 days Clinically important, potentially hazardous interactions with: amitriptyline, amoxapine, benzphetamine, chlorpromazine, clomipramine, desipramine, doxepin, ephedra, ephedrine, imipramine, insulin, insulin glargine, minoxidil, nortriptyline, protriptyline, trimipramine
Reactions
Skin Dermatitis Exanthems Fixed eruption [1] Lupus erythematosus Peripheral edema (>10%) Purpura Urticaria Vasculitis [1]
Hair Hair – alopecia
Other Dizziness [1] Glossitis (5%) Headache Myalgia Paresthesias (16%) Priapism Sialorrhea Xerostomia (1-10%)
