ABSTRACT

Skin Bullous pemphigoid [1] Diaphoresis (<1%) [1] Eczema Edema (1-5%) Erythema multiforme Exanthems (<1%) [1] Exfoliative dermatitis Facial edema (<1%) Hyperkeratosis (palms and soles) Infiltrative dermatitis of the scalp [1] Lichenoid eruption [1] Lupus erythematosus Pityriasis rubra pilaris [1] Pruritus (1-5%) Psoriasis [4] Pustules [1] Rash (sic) (1-5%) Raynaud’s phenomenon (2%) [2] Toxic epidermal necrolysis Urticaria

Xerosis

Hair Hair – alopecia [1]

Nails Nails – dystrophy Nails – onycholysis Nails – pigmentation

Eyes Oculo-mucocutaneous syndrome [1]

Other Dysgeusia Gingivitis [1] Headache Numbness (fingers and toes) (>5%) Oral lichenoid eruption Oral mucosal eruption (<1%) [1] Paresthesias (>5%) Peyronie’s disease [1] Tinnitus Xerostomia (<1%) [1]

*Note: Bendroflumethiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome