ABSTRACT
Trade names: Cin-Quin; Quinalan; Quinora Other common trade names: Cardine; Gluquine; Kinidin; Quinate; Quini Durules Indications: Tachycardia, atrial fibrillation Category: Antiarrhythmic class I A Half-life: 6-8 hours Clinically important, potentially hazardous interactions with: abarelix, amiloride, amiodarone, amprenavir, anisindione, aripiprazole, arsenic, ciprofloxacin, delavirdine, dicumarol, digoxin, duloxetine, enoxacin, fosamprenavir, gatifloxacin, itraconazole, lomefloxacin, moxifloxacin, norfloxacin, ofloxacin, pimozide, pipecuronium, ritonavir, senna, sparfloxacin, telithromycin, vecuronium, verapamil, voriconazole, warfarin
Reactions
Skin Acne [1] Acute generalized exanthematous pustulosis (AGEP) [2]
Allergic reactions (sic) (1%) [1] Angioedema (<1%) Bullous eruption Dermatitis [3] Eczema Erythema multiforme [1] Exanthems [6] Exfoliative dermatitis (<1%) [5] Exudative dermatitis [1] Fixed eruption [1] Flushing (<1%) [2] Granuloma annulare [1] Lichen planus [7] Lichenoid eruption [6] Livedo reticularis (<1%) [5] Lupus erythematosus (<1%) [34] Palmar-plantar desquamation [1] Photosensitivity (<1%) [21] Pigmentation (<1%) [4]
Pruritus (<1%) [3] Psoriasis (<1%) [6] Purpura (1%) [13] Pustules [1] Rash (sic) (1-10%) Side effects (sic) (1%) [1] Subcorneal pustular dermatosis (SneddonWilkinson) [1]
Toxic epidermal necrolysis [2] Urticaria (<1%) [1] Vasculitis (<1%) [4]
Hair Hair – alopecia [1]
Eyes Uveitis [1]
Other Dysgeusia (>10%) (bitter taste) Headache Hypersensitivity [1] Lymphoproliferative disease [1] Myalgia (<1%) Oral mucosal eruption [2]
Porphyria [1] Pseudoporphyria [1]
Tremor (2%)
Trade name: Altace (Monarch) Other common trade names: Delix; Hytren; Pramace; Quark; Ramace; Triatec; Tritace; Unipril Indications: Hypertension Category: Angiotensin-converting enzyme (ACE) inhibitor; Antihypertensive Half-life: 3-17 hours Clinically important, potentially hazardous interactions with: amiloride, spironolactone, triamterene
Reactions
Skin Acne [1] Angioedema (0.3%) [4] Dermatitis (<1%) Diaphoresis (<1%) [2] Dry feeling on face (sic) [1] Edema (<1%) [1] Erythema (circumscribed) [1] Erythema multiforme (<1%) Exanthems [1] Flushing [2] Lichen planus pemphigoides [1] Pemphigus (<1%) [1] Pemphigus foliaceus [1] Photosensitivity (<1%) [3] Pruritus (<1%) [3] Purpura (<1%) Rash (sic) (<1%) [4]
Stevens-Johnson syndrome [1] Urticaria (<1%) Vasculitis (<1%) [1]
Hair Hair – alopecia (1-10%)
Other Ageusia (<1%) Anaphylactoid reactions (<1%) Cough [2] Dysgeusia (<1%) [1] Headache Hypersensitivity (<1%) Paresthesias (<1%) [1] Sialorrhea (<1%) Tinnitus Tremor (<1%) Xerostomia (<1%)
