ABSTRACT

Trade name: Crestor (AstraZeneca) Indications: Hypercholesterolemia, Mixed dyslipidemia Category: Antihyperlipidemic; HMG-CoA reductase inhibitor Half-life: ~19 hours Clinically important, potentially hazardous interactions with: cyclosporine, gemfibrozil, warfarin

Reactions

Skin Flu-like syndrome (2.3%) Infections Peripheral edema (>2%) Pruritus (>1%) Rash (sic) (>2%)

Hematopoietic Ecchymoses (>1%)

Other Abdominal pain (>2%) Anxiety Arthralgia (>2%)

Asthenia (2.7%) Back pain (2.6%) Cough (>2%) Depression (>2%) Dizziness (>2%) Headache (6%) Myalgia (2.8%) Pain (>2%) Paresthesias (>2%) Rhabdomyolysis Rhinitis (2.2%) Sinusitis (2%)