ABSTRACT

Trade name: TNKase (Genentech) Indications: Acute myocardial infarction Category: Recombinant tissue plasminogen activator; Thrombolytic Half-life: 90-130 minutes Clinically important, potentially hazardous interactions with: bivalirudin

Reactions

Skin Angioedema (<1%) Hematomas (local) (12%) Livedo reticularis (<1%) Purple glove syndrome (<1% ) Purpura Rash (sic) (<1%) Urticaria (<1%)

Hematopoietic Ecchymoses

Other Anaphylactoid reactions (<1%) Gangrene (<1%) Rhabdomyolysis (<1%)