ABSTRACT
Other common trade names: Aldocumar; Coumadine; Marevan; Waran; Warfilone Indications: Thromboembolic disease, pulmonary embolism Category: Anticoagulant Half-life: 1.5-2.5 days (highly variable) Clinically important, potentially hazardous interactions with: amiodarone, amobarbital, aprepitant, aprobarbital, arnica, aspirin, azathioprine, azithromycin, bismuth, bivalirudin, bosentan, butabarbital, capsicum, chamomile, cimetidine, clarithromycin, clarithromycin, clofibrate, clopidogrel, clorazepate, co trimoxazole, coenzyme Q-10, cyclosporine, dan-shen, danazol, daptomycin, delavirdine, devil’s claw, dirithromycin, disulfiram, dong quai, erythromycin, evening Primrose, fenofibrate, feverfew, fluconazole, fluoxymesterone, fosamprenavir, garlic, gemfibrozil, ginger, ginkgo biloba, ginseng, glucagon, grapefruit Juice, green tea, guarana, horse chestnut (bark, flower, leaf, seed, imatinib, influenza Vaccines, itraconazole, itraconazole, ketoconazole, levothyroxine, liothyronine, melatonin, mephobarbital, methimazole, methyltestosterone, metronidazole, miconazole, nalidixic acid, peg interferon alfa2b, penicillins, pentobarbital, phenobarbital, phenobarbital, phytonadione, piperacillin, primidone, propoxyphene, propylthiouracil, quinidine, quinine, red clover, rifampin, rifapentine, rifapentine, rofecoxib, rosuvastatin, saw palmetto, secobarbital, st john’s wort, stanozolol, sulfamethoxazole, sulfinpyrazone, sulfisoxazole, sulindac, testosterone, troleandomycin, troleandomycin, valdecoxib, vitamin A, vitamin E, zileuton
Note: Alternative remedies, including herbals, may potentially increase the risk of bleeding or potentiate the effects of warfarin therapy. Some of these include the following: angelica root, arnica flower, anise, asafetida, bogbean, borage seed oil, bromelain, dan shen, devil’s claw, fenugreek, feverfew, garlic, ginger, ginkgo biloba, ginseng, horse chestnut, lovage root, meadowsweet, onion, parsley, passionflower herb, poplar, quassia, red clover, rue, turmeric and willow bark
Reactions
Skin Abscess [1] Acral purpura [1] Angioedema (<1%) Bullous eruption [2] Dermatitis [2] Exanthems [7] Exfoliative dermatitis Hematomas [1] Hemorrhage [3] Lingual hemorrhage [1] Livedo reticularis [1] Necrosis (>10%) [85]
Pruritus (<1%) [2] Purple toe syndrome [1] Purplish erythema (feet and toes) (<1%) [8]
Purpura [3] Rash (sic) (<1%) [1] Ulcerations [1] Urticaria [3] Vasculitis [4] Vesiculation [1]
Hair Hair – alopecia (>10%) [6]
Other Death [1]
Priapism [2]
Scientific name: Pausinystalia yohimbe Family: Rubiaceae Trade and other common names: Actibane (Consolidated Midland); Aphrodyne (Star); Yocon (Palisades); Yohimex (Kramer); Yomax Category: Anesthetic; Aphrodisiac (purported) Purported indications and other uses: Impotence, alpha2-adrenergic blocker, orthostatic hypertension Half-life: 36 minutes
Reactions
Skin Adverse effects (sic) [1] Diaphoresis Exfoliative dermatitis [1] Flushing
Lupus erythematosus [1]
Other Death
