ABSTRACT
Other common trade names: Actilyse; Activacin; Lysatec-rt-PA Indications: Acute myocardial infarction, acute pulmonary embolism Category: Thrombolytic (tissue plasminogen activator) Half-life: 30-45 minutes Clinically important, potentially hazardous interactions with: nitroglycerin, ticlopidine
Reactions
Skin Angioedema [4] Purpura (<1%) [1] Rash (sic) (<0.02%) Urticaria (<1%) [1]
Hematopoietic Ecchymoses (1-10%)
Other Anaphylactoid reactions (<0.02%) [3] Death [1] Gingivitis (<1%) Headache Hypersensitivity [1]
Trade names: Midamor (Merck); Moduretic (Merck) Other common trade names: Amikal; Kaluril; Medamor; Midoride; Modamide; Nirulid; Ride Indications: Prevention of hypokalemia associated with kaliuretic diuretics, management of edema in hypertension Category: Potassium-sparing antihypertensive diuretic Half-life: 6-9 hours Clinically important, potentially hazardous interactions with: benazepril, captopril, cyclosporine, enalapril, fosinopril, lisinopril, moexipril, quinapril, quinidine, ramipril, spironolactone, trandolapril
Moduretic is amiloride and hydrochlorothiazide
Reactions
Skin Diaphoresis Exanthems [1] Flushing (>1%) Photosensitivity [1] Pruritus (<1%) Purpura Rash (sic) (<1%) Urticaria Vasculitis
Xerosis (<1%)
Hair Hair – alopecia (<1%)
Other Anaphylactoid reactions Dysgeusia (<1%) Gynecomastia (1-10%) Headache Paresthesias (<1%)
