ABSTRACT

Contact urticaria is a skin disease with an increasing importance. The usefulness

of products made from natural rubber latex has caused an increase in allergic

(immunologic) contact urticaria, often causing occupational disability. Other

forms of contact urticaria continue to be rather common. The symptoms

experienced in contact urticaria range from local tingling to systemic anaphy-

laxis. The common factor in urticaria is the release of inflammatory mediators

from cutaneous mast cells, which causes pruritus and swelling of the skin tissue.