ABSTRACT

Sjögrens syndrome is an autoimmune disorder predominantly affecting middle-aged or elderly women. The problem is a lymphocytic infiltration into the external secretory glands, which results in atrophy of the acini and consequent reduction of their secretory capacity. There is an increase in mucus transport time. Stasis in the mucus layer is due to the decreased amount of secretion. Normally, particles can become entangled in the mucus, but it seems that in Sjögrens syndrome there is insufficient mucus for this to happen1223.