ABSTRACT
Transgenic Mice and Rats ................................................190 10.5 RNAi Experimental Design Strategy...........................................................191
10.5.1 siRNA/shRNA Design .....................................................................191 10.5.2 Specificity Concerns: Off-Target Effects and the
Interferon Response .........................................................................192 10.5.3 Controls ............................................................................................193
10.6 Conclusion....................................................................................................193 References..............................................................................................................194
