ABSTRACT
Gambieric acids A-D are potent, antifungal compounds obtained from the marine dinoflagellate
Gambierdiscus toxicus
(Nagai et al.,
1992). The antifungal activity of these ladder-shaped polyethers against
Aspergillus niger
is 2000 times greater than that of amphotericin B. Morohashi et al. (2000) determined the absolute configuration of gambieric acids A-D as shown in Scheme G.24.
