Use of Chemically Modified Chitosan and Other Natural-Origin Polymers in Tissue Engineering and Drug Delivery

These materials can combine a reasonable biocompatibility with an intrinsic mechanical performance.

Certain medical applications of chitin and chitosan require physical stability and integrity at surgical site. Glutaraldehyde has been frequently used to crosslink chitosan and was in fact among the first chemical reagent to be able to form a chitosan gel for the immobilization of enzymes.